What If It Happened To You?

IMPORTANT: Please Read Alarming Statement. I was very fortunate to bear witness to an event that all but physically shattered my heart into a thousand pieces today. This event both motivated me and inspired me. Today Tausha had a conversation with her mother, Pat and in this conversation Tausha made a statement expressing that she was so very fortunate. To think so many people gathered and were so willing to do so much for me yesterday. The benefit looked amazing and I am so grateful. I feel awful even thinking this as everyone has been so very great; but do you think now that it has passed that everyone will forget about me, Mom? I still am going to need a great deal of platelets and I feel so selfish to even say any of this. All the supporters of Team Tausha won’t forget about me and the platelets will them?

Team Tausha: Donor Clincs

Having been witness to this selfless woman express guilt for using/needing so many platelets (as she has never asked for a thing in this world) and seeing her struck with fear that Team Tausha might forget about her…. I suddenly became possessed with such motivation and drive to wake up the world and MOTIVATE every single individual who has already donated platelets, thought about donating platelets, or thinking about donating platelets pick up the phone tomorrow and call 713-792-7777 tomorrow and schedule their Team Tausha: Platelet Apt for this week. I know that I ask a great deal of everyone, This Selfless Individual All of Us Know as Team Tausha’ s Very Own Tausha Bowser is so very deserving. If You Haven’t Already Joined The Revolution; We Save Lives Daily, We Make A Difference In A Very Special Person’s Life, & We’re Just Getting Warmed Up.

Please Click the “Share” Share Button Below this post, Please “Like” this Post Below, Please Leave A Comment Below Letting Our Very Own Tausha Bowser Know Just How Much We All Care And How Proud Of Her We Are. Team Tausha: We’re Just Getting Warmed Up! -GW

Garret S. Wilson

Team Tausha: A Life Threatening Disease

PNH—A Life-Threatening Disease

Paroxysmal nocturnal hemoglobinuria (PNH) is a progressive and destructive disease that can cause thrombosis, end-organ damage, and, ultimately, increased mortality.1-3

Moving Forward On this Blog, you can learn more about the pathophysiology of PNH and the signs and symptoms of the disease, examine a series of case studies, read about diagnosis and testing for PNH, and more.

Healthcare providers interested in learning about PNH pathophysiology or diagnosis and testing can get started with the facts about PNH.  Has your doctor diagnosed you with PNH? For information about your condition, a guide to discussing the disease with your doctor, and more, visit the home page for patients with PNH.

Facts About PNH

Paroxysmal nocturnal hemoglobinuria (PNH) is a progressive and destructive disease that can cause thrombosis, end-organ damage, and, ultimately, increased mortality.

PNH Can Be Life Threatening

PNH is a complex disease that presents uniquely in each patient.1-3 The symptoms of PNH include abdominal pain, dyspnea, and fatigue. Because these symptoms are common to many diseases, a diagnosis of PNH is often overlooked. In the meantime, the patient's chance of experiencing serious sequelae of PNH — including thrombosis, chronic kidney disease (CKD) and renal failure, and pulmonary hypertension — grows.

Pathophysiology

PNH is an acquired hematopoietic stem cell disorder in which blood cells lack key, naturally occurring terminal complement inhibitors on the cell surface, rendering them vulnerable to lysis by the membrane attack complex (MAC).4-6

Consequences of Hemolysis

The consequences of hemolysis in PNH can be sudden and potentially fatal.7,8The most common, thromboembolism, can present in typical or atypical sites, can be venous or arterial, and can affect patients young and old.2 Other consequences include CKD, pulmonary hypertension, and end-organ damage.9

Signs & Symptoms

A patient may present with any of the common symptoms of PNH, including abdominal pain, anemia, fatigue, or impaired quality of life (QoL). These symptoms, however, may be indicative of more serious underlying consequences of the disease.

Team Tausha: Join The Revolution

Team Tausha: The First Steps Are Always The Hardest