Clinical Manifestations of PNH

The Diverse and Common Symptomatology of PNH Can Delay Diagnosis,^1,2 Typically From 1 to More Than 10 Years³

The chart below visualizes the PNH symptom incidence rate and the percentage of patients who experience pulmonary hypertension, CKD, and thrombosis.

Next: PNH Case Studies

1. Rosse WF. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al, eds. Hematology: Basic Principles and Practice. 3rd ed. New York, NY: Churchill Livingstone; 2000:331-342. 2. Parker C, Omine M, Richards S, et al; for the International PNH Interest Group. Blood. 2005;106:3699-3709. 3. Dacie JV, Lewis SM. Ser Haematol. 1972;5:3-23. 4. Meyers G, Weitz I, Lamy T, et al. Blood. 2007;110:Abstract 3683. 5. Hill A, Rother R, Wang X, et al. Br J Haematol. 2010;149:414-425. 6. Hillmen P, Elebute M, Kelly R, et al. Am J Hematol. 2010;85:553-559. 7. Hillmen P, Lewis SM, Bessler M, Luzzatto L, Dacie JV. N Engl J Med. 1995;333:1253-1259. 8. Nishimura J-I, Kanakura Y, Ware RE, et al. Medicine. 2004;83:193-207.